Lymph Node Ratio (LNR) Discriminates Prognostication in pN1a-b and pN2 Stage-III Colon Cancer.

ABSTRACT: Background: The lymph node ratio (LNR), involved nodes/ lymph nodes examined, is associated with survival in colon cancer. Previous studies investigated the prognostic role of LNR regardless of TNM N staging or compared LNR and TNM N stages for prognostic strength. However, LNR may be utilized to obtain additional prognostic information rather than replacing TNM staging in daily practice. This study aimed to evaluate the role of LNR in TNM N stages to provide further prognostic information in daily practice. Methods: Patients with stage-III colon cancer who underwent surgery and adjuvant chemotherapy were included. pN1c tumors (tumor deposits without node involvement) and rectal cancers were excluded. Clinicopathological parameters and LNR in pN1a-b and pN2 groups were evalua

SUBMITTER: Akkus E 

PROVIDER: S-EPMC11786040 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature