Evaluation of the Feasibility of Transfusing Leukocyte Depletion Filter-Processed Intraoperative Cell Salvage Blood in Metastatic Spine Tumor Surgery: Protocol for a Non-Randomized Study.

ABSTRACT:

Background

Metastatic spine tumor surgery (MSTS) is often complex and extensive leading to significant blood loss. Allogeneic blood transfusion (ABT) is the mainstay of blood replenishment but with immune-mediated postoperative complications. Alternative blood management techniques (salvaged blood transfusion [SBT]) allow us to overcome such complications. Despite widespread use of intraoperative cell salvage (IOCS) in oncological and nononcological surgical procedures, surgeons remain reluctant to use IOCS in MSTS.

Objective

This study aims to analyze safety of IOCS-leukocyte depletion filter (LDF)-processed blood transfusion for patients undergoing MSTS by assessing clinical outcomes-disease progression: tumor progression and overall survival. This study evaluates whether

SUBMITTER: Kumar N 

PROVIDER: S-EPMC11786134 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature