Analysis of prodromal symptoms and need for short-term prophylaxis in angioedema patients under long-term prophylaxis.

ABSTRACT:

Background

Patients with hereditary angioedema (HAE) experience recurrent, unpredictable episodes of edema. These swellings are often preceded by prodromal symptoms. HAE management includes acute treatment, long-term prophylaxis (LTP), and short-term prophylaxis (STP) before procedures with a risk of swelling. The effects of LTP on prodromal symptoms and the necessity for STP in patients on LTP remain unclear.

Methods

A questionnaire-based study involving HAE and AAE patients receiving LTP was conducted. Changes in prodromal symptoms and the incidence of procedures with an increased risk of swelling, including surgeries, dental procedures, and endoscopies were assessed.

Results

A total of 26 patients were included in the study. Among them, 18 experienced zero to three

SUBMITTER: Lochbaum R 

PROVIDER: S-EPMC11786469 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature