Serum choline, leptin and interleukin-6 levels in fibromyalgia syndrome-induced pain: a case-control study.

ABSTRACT:

Background

Fibromyalgia Syndrome (FMS) predominantly affects middle-aged women, characterized by musculoskeletal pain, fatigue, and cognitive issues. Choline, an endogenous molecule, may influence FMS due to its analgesic and anti-inflammatory properties. This study compared choline, leptin, and interleukin-6 (IL-6) levels in FMS patients and controls and examining their association with pain severity.

Methods

Volunteers with FMS were clinically diagnosed at a Physical Medicine and Rehabilitation Department. The control group included pain-free volunteers. Pain severity was gauged using a numeric scale, dietary choline intake through a questionnaire. Serum choline, leptin and (interleukin)IL-6 levels were measured from fasting blood samples of volunteers with enzyme-linked i

SUBMITTER: Baris E 

PROVIDER: S-EPMC11786483 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature