Optimization and characterization of bioactive secondary metabolites from Streptomyces sp CMSTAAHL-4 isolated from mangrove sediment.

ABSTRACT:

Background

Ten morphologically different actinomycetes were isolated from mangrove sediments of Manakudy, Kanyakumari District, India. The potent strain was selected based on their primary screening against Gram positive Staphylococcus aureus, Enterococcus faecalis and Gram negative Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi bacterial pathogens. The selected strain was identified as Streptomyces sp CMSTAAHL-4 by 16S rRNA sequencing. The media optimization for secondary metabolites production was performed by One-Variable at a Time and Response Surface Methodology-Central Composite Design. Minimum inhibitory concentration and minimum bacterial concentration for the extracted secondary metabolites were determined. The antioxidant potential of th

SUBMITTER: Nisha SJ 

PROVIDER: S-EPMC11786576 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature