Enhancing laboratory test consistency through linear transformation: A multi-center study.

ABSTRACT:

Objectives

China is promoting the mutual recognition of clinical laboratory test results to reduce redundant testing, provide more convenient medical services, and lower economic burdens. This study aimed to enhance the consistency of test results across laboratories using a linear transformation method, focusing on five representative biochemical parameters: ALP, CA, TBIL, TC, and TG.

Methods

Five ISO 15189 accredited laboratories participated in this study. We established inter-laboratory and intra-laboratory conversion relationships using patient sample comparisons and daily quality control (QC) data. These relationships were used to develop a web-based tool enabling real-time conversion and mutual recognition of laboratory test results.

Results

The study found tha

SUBMITTER: Cheng S 

PROVIDER: S-EPMC11786656 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature