Electrostimulation combined with biodegradable electroactive oriented nanofiber polycaprolactone/gelatin/carbon nanotube to accelerate wound healing.

ABSTRACT: Wound healing is a complex but precise physiological process. Howener, existing treatments are often difficult to meet the needs of different wound healing. With the background that exogenous electrical stimulation (ES) has been proven to be effective in regulating cell behavior, we constructed a electroactive wound dressing derived from carbon nanotubes (CNT) by electrospinning technology. The scaffold has a moderate hydrophilicity, which benefits to collecting of effusion, adhering to the wound site, and safely removing. Furthermore, the oriented structure has the potential to promote cell oriented growth, while the coupling of endogenous electric field (EFs) and ES could effectively regulate the phenotype of macrophages and reshape the immune microenvironment. At the same time, the acti

SUBMITTER: Chen W 

PROVIDER: S-EPMC11786698 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature