Detection of necrotic enteritis risk through non-invasive monitoring of Clostridium perfringens in feces.

ABSTRACT: Necrotic enteritis (NE), caused by the gram-positive, anaerobic bacterium, Clostridium perfringens, results in an estimated $6 billion in annual economic losses to the global poultry industry. C. perfringens is part of the normal microflora of the poultry gastrointestinal tract, but damage to the intestinal epithelium can lead to increased cell proliferation and production of toxins which gives rise to disease. Conventional methods to diagnose NE are invasive and are typically performed after the disease has manifested. In a pen trial using a necrotic enteritis model, we demonstrate that non-invasive monitoring in feces can detect an increase in average C. perfringens counts that correlates with higher lesion scores and reduced body weight gain in birds with NE. This was achieved using a C

SUBMITTER: Shidore T 

PROVIDER: S-EPMC11786763 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature