Evaluation of biological performance of 3D printed trabecular porous tantalum spine fusion cage in large animal models.

ABSTRACT:

Background

The materials for artificial bone scaffolds have long been a focal point in biomaterials research. Tantalum, with its excellent bioactivity and tissue compatibility, has gradually become a promising alternative material. 3D printing technology shows unique advantages in designing complex structures, reducing costs, and providing personalized customization in the manufacture of porous tantalum fusion cages. Here we report the pre-clinical large animal (sheep) study on the newly developed 3D printed biomimetic trabecular porous tantalum fusion cage for assessing the long-term intervertebral fusion efficacy and safety.

Methods

Porous tantalum fusion cages were fabricated using laser powder bed fusion (LPBF) and chemical vapor deposition (CVD) methods. The fusion cage

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11786794 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature