Association between social determinants of health and premature atherosclerotic cardiovascular disease and sex differences in US adults: A cross-sectional study.

ABSTRACT:

Background

Premature atherosclerotic cardiovascular disease (ASCVD) is a major public health issue, leading to productivity losses and higher healthcare costs. This study examines the association between social determinants of health (SDoH) and premature ASCVD, with a focus on sex differences.

Method

Data on self-reported SDoH based on Healthy People 2030 criteria were obtained from U.S. National Health and Nutrition Examination Surveys (2003-2018). Weighted logistic regression models were used to examine the relationship between SDoH (including eight sub-items and the cumulative number of unfavorable SDoH) and premature ASCVD. Analyses were further stratified by sex.

Result

A total of 40,536 participants aged ≥18 years (19,548 men and 20,888 women) were included in t

SUBMITTER: Yang C 

PROVIDER: S-EPMC11786895 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature