Incident Heart Failure in Atherosclerotic Renal Artery Stenosis: A Post Hoc Analysis of the CORAL Trial.

ABSTRACT:

Rationale & objective

Although renal artery stenosis (RAS) and heart failure (HF) have been linked, the incidence and predictors of HF among patients with RAS are not well described.

Study design

Post hoc analysis of the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) multicenter, open-label, randomized controlled trial (RCT).

Settings and participants

Patients with atherosclerotic RAS and elevated blood pressure, chronic kidney disease, or both, and without a history of HF at enrollment.

Intervention

Medical therapy alone versus medical therapy plus renal artery stenting.

Outcomes

Incident HF events.

Results

This analysis included 808 participants enrolled in the CORAL trial without evidence of baseline HF. During a median follow

SUBMITTER: Gupta R 

PROVIDER: S-EPMC11787008 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature