Ontology highlight
ABSTRACT: Background
Dyslipidemia is a primary risk factor for cardiovascular disease (CVD). Exercise training (EXTr) improves some lipid markers but not others; the literature is dated and analyses may be underpowered.Objectives
To clarify which lipid markers are altered with ExTr and establish if information size had yet reached futility.Methods
We conducted a systematic review/meta-analysis, with meta-regression, to establish expected effect size in lipid profile with aerobic (AT), resistance (RT) and combined (CT = AT + RT) ExTr. We conducted trial sequence analysis (TSA) to control for type I and II error and establish if information size had reached futility.Results
We included 148 relevant randomized controlled trials (RCTs) of ExTr, with 227 intervention group
SUBMITTER: Smart NA
PROVIDER: S-EPMC11787149 | biostudies-literature | 2025 Jan
REPOSITORIES: biostudies-literature