The role of viral interaction in household transmission of symptomatic influenza and respiratory syncytial virus.

ABSTRACT: The role of viral interaction-where one virus enhances or inhibits infection with another virus-in respiratory virus transmission is not well characterized. This study used data from 4029 total participants from 957 households who participated in a prospective household cohort study in Southeast Michigan, U.S.A to examine how viral coinfection and cocirculation may impact transmission of symptomatic influenza and respiratory syncytial virus infections. We utilized multivariable mixed effects regression to estimate transmission risk when index cases were coinfected with multiple viruses and when viruses cocirculated within households. This analysis included 201 coinfections involving influenza A virus, 67 involving influenza B virus, and 181 involving respiratory syncytial virus. We show th

SUBMITTER: Ibiebele JC 

PROVIDER: S-EPMC11787320 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature