Testicular function in postpubertal patients with growth hormone deficiency: A prospective controlled study.

ABSTRACT:

Background

We have previously shown that treatment with recombinant human growth hormone (GH) influences testicular growth in children with GH deficiency (GHD) and have suggested that GH plays a role in testicular growth in childhood. Little evidence is available on testicular function in post-pubertal GHD patients.

Objective

This prospective controlled study was undertaken to evaluate testicular function in patients with GHD.

Patients and methods

Post-pubertal patients with non-syndromic GHD over the age of 16 years were enrolled. Each patient underwent to the assessment of serum levels of gonadotropins and total testosterone (TT), conventional sperm parameters, and testicular volume (TV) measured by ultrasound examination. Age-matched healthy subjects served as cont

SUBMITTER: Cannarella R 

PROVIDER: S-EPMC11787440 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature