Genomic epidemiology of third-generation cephalosporin-resistant Escherichia coli from companion animals and human infections in Europe.

ABSTRACT: In high-income countries, dogs and cats are often considered members of the family. Because of this proximity, it has been suggested that pets and humans might exchange bacterial species from their gut microbiota, with multidrug resistant bacteria being of particular concern. The aim of this study was to compare the genomes of third-generation cephalosporin-resistant (3GC-R) Escherichia coli responsible for human and pet infections in Europe. Whole-genome sequencing data from 3GC-R E. coli isolated from clinical samples of humans, dogs and cats, and published in eight European studies were re-analyzed using bioinformatics tools. The acquired genes responsible for 3GC-R were identified. The sequence type (ST) of all genomes were assessed by multilocus sequence typing. Alpha an

SUBMITTER: Biguenet A 

PROVIDER: S-EPMC11787529 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature