Patients with Age-related Macular Degeneration Have Increased Susceptibility to Valvular Heart Disease.

ABSTRACT:

Purpose

Valvular heart disease (VHD) contributes significantly to cardiovascular-related morbidity worldwide. Aortic valve stenosis is the third most common cardiovascular disease in the Western world, after hypertension and coronary artery disease. Recent studies have reported an association between VHD and the presence of subretinal drusenoid deposits (SDDs), a distinct manifestation of age-related macular degeneration (AMD). However, these findings were based on self-reported questionnaires and relatively modest cohort sizes. Our goal was therefore to investigate the putative associations between AMD and VHD and between the presence of SDDs and VHD.

Design

Retrospective case-control study.

Subjects

A total of 945 with AMD and 8275 control patients without AMD from

SUBMITTER: Lishinsky-Fischer N 

PROVIDER: S-EPMC11787562 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature