Effectiveness of late and very late antivenom administration on recovery from snakebite-induced coagulopathy in French Guiana: a population-based study.

ABSTRACT:

Background

Snakebite (SB) envenoming is an acute emergency requiring early care delivery. However, sometimes, patients can take several hours before receiving antivenom (AV). We conducted this study to assess the effectiveness of antivenom in the recovery of clotting parameters in patients consulting tardily after SB envenoming in French Guiana. The primary endpoint of our study was to investigate the time needed from SB to recovery from SB-induced coagulopathy. The secondary endpoint was to investigate the time needed from AV administration to recovery from SB-induced coagulopathy in patients receiving AV (late or very late administration).

Methods

This prospective observational study was conducted in the Intensive Care Unit (ICU) of Cayenne General Hospital between January

SUBMITTER: Pujo JM 

PROVIDER: S-EPMC11787608 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature