Complete blood count in neonatal Intensive care Unit (NICU): Performance comparison between POCT Sight OLO® and Sysmex XN-9100™ hematology analyzers.

ABSTRACT:

Background and aims

The use of a POCT (Point Of Care Test) could help in reducing the impact of pre-analytical errors in particular in challenging newborn samples.The study purpose is to compare the POCT Sight OLO® hematology analyzer, validated for >3 months patients, with the reference system Sysmex XN-9100™ in Neonatal Intensive Care Unit (NICU).

Material and methods

The two analyzers were compared through Passing-Bablok regression analysis and Bland-Altman plot.

Results

We analyzed 65 blood samples, in detail 38 from adults and 27 from newborns.The regression analysis results performed in the newborn and adult patients showed a good agreement between the two instruments. The evaluation of the Bland-Altman plots showed comparable values of bias <10 % for the most o

SUBMITTER: Nencini F 

PROVIDER: S-EPMC11787615 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature