Non - Invasive, smartphone image-based screening for sickle cell disease at the point-of-need.

ABSTRACT: Leveraging the increasing accessibility of smartphones in healthcare settings, we developed a smartphone app aimed at enhancing sickle cell disease (SCD) screening, particularly in resource-limited settings. Our application provides accurate and non-invasive SCD screening with instant results at the point-of-need. The app operates by analyzing patient fingernail images via a smartphone image to gauge anemia severity and by using targeted inquiries to identify SCD-related symptoms. These inputs collectively generate an SCD IMage and Patient profile-based Likelihood Estimation (SIMPLE) score, which estimates disease probability. The accuracy of the score depends on two inputs: the patient's anemia status and their health survey responses. We tested the app

SUBMITTER: Vital EF 

PROVIDER: S-EPMC11787632 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature