Evaluation of phytochemical composition, antioxidant, cytotoxic and in silico studies of ethyl acetate fractions of Tristaniopsis merguensis leaves.

ABSTRACT: Tristaniopsis merguensis is a member of the Myrtaceae family. The leaves of T. merguensis are frequently utilized as herbal tea. The study aimed to evaluate the polyphenolic content, antioxidant, and cytotoxic properties of ethyl acetate fractions derived from Tristaniopsis merguensis (ETM). In addition, it also aimed to conduct an LC-HRMS analysis of a potential fraction to ascertain its suitability as an antioxidant and anticancer active ingredient. An antioxidant evaluation was carried out using the ABTS and DPPH methods. Meanwhile, an in silico study was performed using the target protein elastase (HER-2). A total of twenty metabolites of T. merguensis were identified in the potential fraction ETM.05. In antioxidant testing, the T. merguensis f

SUBMITTER: Situmeang B 

PROVIDER: S-EPMC11787705 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature