Serum salusin levels in diarrhea- and constipation-predominant irritable bowel syndrome.

ABSTRACT:

Objective

Inflammation and immunity play major roles in the etiopathogenesis of functional intestinal disorders. The salusins that were identified in this study are important because of their ease of collection, sensitivity and reliability. For that reason, the aim of this study was to analyze the importance of the levels of salusin in the blood, an inflammation-related parameter, in the diagnosis and prediction of irritable bowel disease.

Methodology

The study participants included 28 diagnosed with constipation-predominant IBS, 29 (34.1%) diagnosed with diarrhea-predominant IBS (D-IBS), and 28 (32.9%) controls. Enzyme-linked immune-sorbent assay (ELISA) method has been used for the measurement of salusin levels.

Results

Participants were 50 (58.8%) female and 35 (41

SUBMITTER: Tuncel ET 

PROVIDER: S-EPMC11787801 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature