A case of penicillin-resistant group B Streptococcus isolated from a patient in the UK.

ABSTRACT:

Objectives

In England, group B streptococci (GBS; Streptococcus agalactiae) are considered universally susceptible to penicillin. Reports from Africa, Asia, North America and a few European countries have described GBS isolates with penicillin MICs above the epidemiological cut-off (0.125 mg/L). Our aim was to characterize a penicillin-resistant GBS (PRGBS) isolate recovered in 2016 from a patient treated with long-term antimicrobials in the UK.

Methods

Antibiotic susceptibility of a referred isolate from a discharging sinus overlying a chronic prosthetic joint infection was determined using gradient strip testing for seven antibiotics. Illumina short read sequencing was carried out using a HiSeq 2500 platform to determine MLST, capsular type, to detect mutations in the pbp

SUBMITTER: McGuire E 

PROVIDER: S-EPMC11787890 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature