On the acceptance, commissioning, and quality assurance of electron FLASH units.

ABSTRACT:

Background and purpose

FLASH or ultra-high dose rate (UHDR) radiation therapy (RT) has gained attention in recent years for its ability to spare normal tissues relative to conventional dose rate (CDR) RT in various preclinical trials. However, clinical implementation of this promising treatment option has been limited because of the lack of availability of accelerators capable of delivering UHDR RT. Commercial options are finally reaching the market that produce electron beams with average dose rates of up to 1000 Gy/s. We established a framework for the acceptance, commissioning, and periodic quality assurance (QA) of electron FLASH units and present an example of commissioning.

Methods

A protocol for acceptance, commissioning, and QA of UHDR linear accelerators was establi

SUBMITTER: Palmiero A 

PROVIDER: S-EPMC11788050 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature