Functional mapping of movement and speech using task-based electrophysiological changes in stereoelectroencephalography.

ABSTRACT:

Objective

Stereoelectroencephalography (SEEG) has become the predominant method for intracranial seizure localization. When imaging, semiology, and scalp EEG findings are not in full agreement or definitively localizing, implanted SEEG recordings are used to test candidate seizure onset zones (SOZs). Discovered SOZs may then be targeted for resection, laser ablation, or neurostimulation. If an SOZ is eloquent, resection and ablation are both contraindicated, so identifying functional representation is crucial for therapeutic decision-making. The authors present a novel functional brain mapping technique that utilizes task-based electrophysiological changes in SEEG during behavioral tasks and test this in pediatric and adult patients.

Methods

SEEG was recorded in 20 patients

SUBMITTER: Jensen MA 

PROVIDER: S-EPMC11788070 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature