Myocardial perfusion SPECT radiomic features reproducibility assessment: Impact of image reconstruction and harmonization.

ABSTRACT:

Background

Coronary artery disease (CAD) has one of the highest mortality rates in humans worldwide. Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) provides clinicians with myocardial metabolic information non-invasively. However, there are some limitations to interpreting SPECT images performed by physicians or automatic quantitative approaches. Radiomics analyzes images objectively by extracting quantitative features and can potentially reveal biological characteristics that the human eye cannot detect. However, the reproducibility and repeatability of some radiomic features can be highly susceptible to segmentation and imaging conditions.

Purpose

We aimed to assess the reproducibility of radiomic features extracted from uncorrected M

SUBMITTER: Gharibi O 

PROVIDER: S-EPMC11788242 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature