Monte Carlo dose calculation for photon and electron radiotherapy on dynamically deforming anatomy.

ABSTRACT:

Background

Dose calculation in radiotherapy aims to accurately estimate and assess the dose distribution of a treatment plan. Monte Carlo (MC) dose calculation is considered the gold standard owing to its ability to accurately simulate particle transport in inhomogeneous media. However, uncertainties such as the patient's dynamically deforming anatomy can still lead to differences between the delivered and planned dose distribution.

Purpose

Development and validation of a deformable voxel geometry for MC dose calculations (DefVoxMC) to account for dynamic deformation in the dose calculation process of photon- and electron-based radiotherapy treatment plans for clinically motivated cases.

Methods

DefVoxMC relies on the subdivision of a regular voxel geometry into dodec

SUBMITTER: Zobrist B 

PROVIDER: S-EPMC11788255 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature