Heat-not-burn technology affects plasma testosterone levels and markers of inflammation, oxidative stress in the testes of rats.

ABSTRACT:

Introduction

Heating tobacco products (HTPs) are advanced electronic cigarette models. Classified by the FDA as a modified-risk tobacco product and can be used as part of efforts to quit smoking. Using heat-not-burn (HnB) technology, these devices heat tobacco avoiding complete combustion. Although the levels of toxicants in the mainstream are significantly lower than those observed in tobacco smoke, some recent studies have raised concerns about potential health risks associated with their use, particularly regarding their effects on male gonadal function, which remain largely unexplored.

Methods

Adult male Sprague-Dawley rats were exposed, whole body, 5 days/week for 4 weeks to HnB mainstream.

Results

The expression of the cell cycle regulators Bax/Bcl-2 ratio is no

SUBMITTER: Granata S 

PROVIDER: S-EPMC11788375 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature