Risk factors of dementia in a cohort of individuals with mild cognitive impairment in the Italian Interceptor project.

ABSTRACT:

Background

The Italian Interceptor project is aimed at identifying a prodromal dementia phase and developing a nationwide organizational model. This study compares the sociodemographic and neuropsychological characteristics of mild cognitive impairment non-converters (MCI-NC) and MCI-converters (MCI-C) to dementia, including Alzheimer's disease (AD), enrolled during the Interceptor project.

Methods

Sociodemographic, clinical, and neuropsychological data of MCI individuals were collected at baseline (December 2018 to October 2020) and every six-month follow-up visit for 3 years. Logistic regression and Random Forest classifier were used to describe the study population.

Results

From 356 participants, 104 were MCI-C, whereas 252 were MCI-NC. Compared to MCI-NC, MCI-C we

SUBMITTER: Carrarini C 

PROVIDER: S-EPMC11788538 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature