Plasma microRNA-145-5p as a diagnostic biomarker for acute deep vein thrombosis.

ABSTRACT:

Background

Identification of new biomarkers for acute deep vein thrombosis (DVT) that could lower the need for diagnostic imaging to confirm or rule out the diagnosis would be advantageous. microRNA-145-5p (miR-145) has the potential to be a diagnostic marker for acute DVT, but its diagnostic performance has not been evaluated in consecutive patients referred to the hospital with suspected DVT.

Objectives

The aim of this study was to assess the diagnostic performance of miR-145 for the diagnosis of acute lower extremity DVT.

Methods

Patients consecutively referred to the emergency room at Akershus University Hospital (Norway) due to suspicion of acute DVT between June 2021 and July 2023 were included. Within 24 hours of admission, blood was collected for assessment of

SUBMITTER: Antoun C 

PROVIDER: S-EPMC11788850 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature