Adaptive evolutionary trajectories in complexity: Transitions between unicellularity and facultative differentiated multicellularity.

ABSTRACT: Multicellularity spans a wide gamut in terms of complexity, from simple clonal clusters of cells to large-scale organisms composed of differentiated cells and tissues. While recent experiments have demonstrated that simple forms of multicellularity can readily evolve in response to different selective pressures, it is unknown if continued exposure to those same selective pressures will result in the evolution of increased multicellular complexity. We use mathematical models to consider the adaptive trajectories of unicellular organisms exposed to periodic bouts of abiotic stress, such as drought or antibiotics. Populations can improve survival in response to the stress by evolving multicellularity or cell differentiation-or both; however, these responses have associated costs when the stre

SUBMITTER: Isaksson H 

PROVIDER: S-EPMC11789074 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature