Characterizing disrupted nighttime sleep and associated functional outcomes in youth with narcolepsy type 1.

ABSTRACT:

Study objectives

Disrupted nighttime sleep and sleep instability are common in children and adolescents with narcolepsy type 1, but optimal objective sleep measures have not been determined. We compared self-reported and objective sleep measures between young people with narcolepsy type 1 and healthy controls and test the hypotheses that the wake/non-rapid eye movement sleep stage 1 (N1) index is the best objective measure of perceived nocturnal wakings vs other disrupted nighttime sleep measures reported in the literature and is associated with daytime functional problems.

Methods

n = 26 healthy controls and n = 27 narcolepsy type 1 participants ages 8-21 years completed a 15-item habitual sleep quality survey and an in-lab polysomnogram. We compared group survey responses

SUBMITTER: Heckler G 

PROVIDER: S-EPMC11789264 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature