L-shaped association of body mass index with prognosis in individuals with sepsis: a multicenter cohort study.

ABSTRACT:

Objective

The relationship between body mass index (BMI) and sepsis prognosis remains highly controversial and uncertain. This study investigated the association between BMI and prognosis in patients with sepsis.

Methods

This retrospective observational cohort study included adult patients admitted to the intensive care unit (ICU) with sepsis from Medical Information Mart for Intensive Care-IV version 2.2 (MIMIC-IV V2.2) and eICU Collaborative Research Database (eICU-CRD). The cut-off value of BMI was identified by the restricted cubic spline (RCS) curve and included patients were categorized into two groups: the low BMI group (< 28 kg/m²) and the high BMI group (≥ 28 kg/m²). The primary outcome was ICU mortality, and secondary outcomes were in-hospital

SUBMITTER: Cui K 

PROVIDER: S-EPMC11789304 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature