Patients with chronic heart failure and predominant left atrial versus left ventricular myopathy.

ABSTRACT:

Background

Left atrial (LA) and ventricular (LV) functional impairment often co-exist in patients with heart failure (HF). However, some patients with HF have a disproportionate LA or LV dysfunction. We aimed to characterize patients with predominant LA and LV myopathy in a cohort of patients with chronic HF across the spectrum of LV ejection fraction (LVEF).

Methods

From a nationwide, prospective, multi-center, observational HF cohort, transthoracic echocardiographic examination was performed on each patient. LA reservoir strain and LV global longitudinal strain (LVGLS) were measured using dedicated software of the two-dimensional speckle tracking analysis to evaluate LA and LV function and to define the myopathy.

Results

A total of 374 patients with chronic HF (mean

SUBMITTER: Jin X 

PROVIDER: S-EPMC11789358 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature