Thyroid function abnormalities in individuals with sickle cell disease: a meta-analysis.

ABSTRACT:

Background

There has been an increasing comprehension and recognition of endocrine dysfunction among both pediatric and adult patients with sickle cell disease (SCD). Thyroid disorders can have significant clinical consequences, including growth retardation and impaired cognitive function. However, there is a disparity in the available data concerning the magnitude and spectrum of thyroid abnormalities in this population. This review aimed to provide a systematic summary and analyses on the status of thyroid function abnormalities in individuals with SCD.

Methods

Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a comprehensive search was conducted across Medline/PubMed, Google Scholar, World Health Organization Virtual Hea

SUBMITTER: Mohamed SOO 

PROVIDER: S-EPMC11789372 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature