The chromatin landscape of the histone-possessing <i>Bacteriovorax</i> bacteria.

ABSTRACT: Histone proteins have traditionally been thought to be restricted to eukaryotes and most archaea, with eukaryotic nucleosomal histones deriving from their archaeal ancestors. In contrast, bacteria lack histones as a rule. However, histone proteins have recently been identified in a few bacterial clades, most notably the phylum Bdellovibrionota, and these histones have been proposed to exhibit a range of divergent features compared with histones in archaea and eukaryotes. However, no functional genomic studies of the properties of Bdellovibrionota chromatin have been carried out. In this work, we map the landscape of chromatin accessibility, active transcription, and three-dimensional (3D) genome organization in a member of Bdellovibrionota (a Bacteriovorax strain). We find that, sim

SUBMITTER: Marinov GK 

PROVIDER: S-EPMC11789641 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature