Association between subtypes of diabetes and special sensations: A 2-sample Mendelian randomization study.

ABSTRACT: Diabetes, a chronic condition affecting millions of individuals, is divided into type 1 diabetes (T1D) and type 2 diabetes (T2D), each with unique pathophysiological characteristics. While the impact of diabetes on vision is established, its relationship with other special senses, balance, hearing, and olfaction, remains uncertain. This study utilized a 2-sample Mendelian randomization (MR) approach to investigate the associations between diabetes subtypes and specific sensory disorders. We performed MR analysis using various methods (inverse variance weighting [IVW], MR-Egger, simple mode, weighted mode, weighted median, MR-PRESSO) to assess the causal relationships between diabetes subtypes and sensory disorders (vestibular dysfunction, sensorineural hearing loss, conductive hearing loss

SUBMITTER: Liu S 

PROVIDER: S-EPMC11789867 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature