Topical Photodynamic Therapy in a Medical Centre: The Scottish Dermatology Experience.

ABSTRACT:

Background

Topical photodynamic therapy (PDT) is widely used in dermatology for treating superficial non-melanoma skin cancer (NMSC) and dysplasia. This study aims to assess real-world outcomes of PDT in a Scottish dermatology service.

Methods

We retrospectively reviewed patients with superficial NMSC and dysplasia who underwent conventional and daylight PDT at the Photobiology Unit, Dundee, Scotland.

Results

A total of 705 patients with 2108 NMSC and precancerous skin lesions underwent conventional PDT. Clearance at 12 months was achieved in 53.4% of actinic keratoses (AK), 71.3% of Bowenoid AK, 86.4% of Bowen's disease (BD), 89.0% of superficial basal cell carcinoma (BCC), and 89.7% of nodular BCC. On multivariate analysis, small lesion size and thin histological tu

SUBMITTER: Chaiyabutr C 

PROVIDER: S-EPMC11790065 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature