Transition of clinical biomarker status from childhood into adolescence-A prospective study in children from eight European countries.

ABSTRACT:

Purpose

Understanding factors influencing clinical biomarkers is important for the prevention of chronic disease. This study aimed to estimate transitions of biomarker status from childhood to adolescence and to identify determinants of biomarker status in early life in a prospective children cohort.

Subjects and methods

Our sample comprised 1295 children participating in the baseline (2007/08) and second follow-up examination (2013/14) of the multi-center IDEFICS (Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS)/I.Family study. Clinical blood biomarkers including glycated hemoglobin A1c (HbA1c), high-density lipoprotein cholesterol (HDL-cholesterol), triglycerides, C-reactive protein (CRP), interleukin 6, ferritin, lept

SUBMITTER: Floegel A 

PROVIDER: S-EPMC11790143 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature