The impacts of antipsychotic medications on eating-related outcomes: A mixed methods systematic review.

ABSTRACT:

Background

Almost all antipsychotics are associated with weight gain. Given the gravity of this side-effect and its consequences, it is imperative to understand the mechanisms involved. One mechanism that could contribute to this side effect is the impact of antipsychotics on eating-related outcomes.

Objective

We aimed to synthesise the available quantitative research on the effects of first- and second-generation antipsychotics on eating-related outcomes, and qualitative research exploring people's experiences with these medications in relation to appetite and eating behaviours (PROSPERO protocol CRD42022340211).

Methods

We searched Medline, PsycInfo, and Web of Science from inception to 9 May 2024. Quantitative data were synthesised without meta-analysis using vote

SUBMITTER: Alkholy R 

PROVIDER: S-EPMC11790239 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature