Genetic Transfer in Action: Uncovering DNA Flow in an Extremophilic Microbial Community.

ABSTRACT: Horizontal genetic transfer (HGT) is a significant driver of genomic novelty in all domains of life. HGT has been investigated in many studies however, the focus has been on conspicuous protein-coding DNA transfers that often prove to be adaptive in recipient organisms and are therefore fixed longer-term in lineages. These results comprise a subclass of HGTs and do not represent exhaustive (coding and non-coding) DNA transfer and its impact on ecology. Uncovering exhaustive HGT can provide key insights into the connectivity of genomes in communities and how these transfers may occur. In this study, we use the term frequency-inverse document frequency (TF-IDF) technique, that has been used successfully to mine DNA transfers within real and simulated high-quality prokaryote genomes, to searc

SUBMITTER: Van Etten J 

PROVIDER: S-EPMC11790422 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature