Time Restricted Eating: A Valuable Alternative to Calorie Restriction for Addressing Obesity?

ABSTRACT:

Purpose of review

In this review, we summarize the molecular effects of time-restricted eating (TRE) and its possible role in appetite regulation. We also discuss the potential clinical benefits of TRE in obesity.

Recent findings

TRE is an emerging dietary approach consisting in limiting food intake to a specific window of time each day. The rationale behind this strategy is to restore the circadian misalignment, commonly seen in obesity. Preclinical studies have shown that restricting food intake only during the active phase of the day can positively influence several cellular functions including senescence, mitochondrial activity, inflammation, autophagy and nutrients' sensing pathways. Furthermore, TRE may play a role by modulating appetite and satiety hormones, though fu

SUBMITTER: Parrotta ME 

PROVIDER: S-EPMC11790783 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature