Association of epicardial adipose tissue volume with heart weight in post-mortem cases.

ABSTRACT: Epicardial adipose tissue (EAT) deposition has been long associated with heart weight. However, recent research has failed to replicate this association. We aimed to determine the association of EAT volume with heart weight in post-mortem cases and identify potential confounding variables. EAT volume derived from post-mortem computed tomography (PMCT) and heart weight were measured in post-mortem cases (N = 87, age: 56 ± 16 years, 28% female). Cases with hypertrophied heart weights (N = 44) were determined from reference tables. Univariable associations were tested using Spearman correlation and simple linear regression. Independence was determined with stepwise regression. In the total cohort, EAT volume (median 66 ± 45 cm³) was positively associated with heart weight (median 4

SUBMITTER: Aitken-Buck HM 

PROVIDER: S-EPMC11790810 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature