Optical widefield nuclear magnetic resonance microscopy.

ABSTRACT: Microscopy enables detailed visualization and understanding of minute structures or processes. While cameras have significantly advanced optical, infrared, and electron microscopy, imaging nuclear magnetic resonance (NMR) signals on a camera has remained elusive. Here, we employ nitrogen-vacancy centers in diamond as a quantum sensor, which converts NMR signals into optical signals that are subsequently captured by a high-speed camera. Unlike traditional magnetic resonance imaging, our method records the NMR signal over a wide field of view in real space. We demonstrate that our optical widefield NMR microscopy can image NMR signals in microfluidic structures with a ~10 μm resolution across a ~235 × 150 μm² area. Crucially, each camera pixel records an NMR spectrum providing mul

SUBMITTER: Briegel KD 

PROVIDER: S-EPMC11790880 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature