Sensorimotor environment but not task rule reconfigures population dynamics in rhesus monkey posterior parietal cortex.

ABSTRACT: Primates excel at mapping sensory inputs flexibly onto motor outcomes. We asked if the neural dynamics to support context-sensitive sensorimotor mapping generalizes or differs between different behavioral contexts that demand such flexibility. We compared reaching under mirror-reversed vision, a case of adaptation to a modified sensorimotor environment (SE), with anti reaching, a case of applying an abstract task rule (TR). While neural dynamics in monkey posterior parietal cortex show shifted initial states and non-aligned low-dimensional neural subspaces in the SE task, remapping is achieved in overlapping subspaces in the TR task. A recurrent neural network model demonstrates how output constraints mimicking SE and TR tasks are sufficient to generate the two fundamentally different neur

SUBMITTER: Guo H 

PROVIDER: S-EPMC11791165 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature