Neutrophils as indicators of obesity-associated inflammation: A systematic review and meta-analysis.

ABSTRACT:

Introduction

The aim of this study is to evaluate and compare the suitability of routine blood neutrophil values as indicators of obesity-associated inflammation.

Methods

In this systematic review and meta-analysis, we assess absolute neutrophil counts (ANCs) and neutrophil-to-lymphocyte ratio (NLR) values in subjects with and without obesity and analyze the weight of both parameters on the disease. Additionally, correlation studies between ANC and NLR with BMI, a parameter internationally accepted to define obesity are performed.

Results

Quantitative data from 12 (ANC) and 11 (NLR) studies were included, with a total of 4475 participants. The meta-analysis shows that while both parameters are increased in the obesity group, ANC values present higher differences with

SUBMITTER: Gomez-Casado G 

PROVIDER: S-EPMC11791391 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature