Prophylactic Aspirin Dose and Preeclampsia.

ABSTRACT:

Importance

It is unclear whether a higher dose (150-160 mg) or a lower dose (75 mg) of aspirin should be used to prevent preeclampsia.

Objectives

To compare the risk of preeclampsia and bleeding complications between women using 150 to 160 mg of aspirin and those using 75 mg of aspirin for preeclampsia prevention.

Design, setting, and participants

This nationwide cohort study included 13 828 women giving birth at 22 weeks' gestation or later in Sweden between January 2017 and December 2020 who used low dose aspirin (75-160 mg) during pregnancy. Data were analyzed from October to November 2023.

Exposure

The use of 150 to 160 mg or 75 mg of aspirin in pregnancy.

Main outcome and measures

The main outcome was a preeclampsia diagnosis recorded in the materna

SUBMITTER: Kupka E 

PROVIDER: S-EPMC11791696 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature