Unexpectedly high variability in determining tumour extent in prostatic biopsies: implications for active surveillance.

ABSTRACT:

Aims

Tumour content in prostatic biopsies is an important indicator of prostate cancer volume and patient prognosis. Consequently, guidelines typically recommend reporting it as a percentage or linear length (mm). This study aimed to determine the current practices for reporting tumour content in prostatic biopsies and evaluated the consistency among pathologists in diagnosing 10 standard biopsy cases of prostate cancer to assess interobserver variability.

Methods and results

A web-based survey gathered data on demographics, experience and attitudes regarding the reporting of prostate cancer and its extent in biopsies. Virtual microscopy allowed analysis of 10 biopsy cases, each consisting of a single slide of prostate cancer. Self-reports from 304 participants recruited via

SUBMITTER: Bernhardt M 

PROVIDER: S-EPMC11791730 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature