Distal C-H functionalization of alkoxyarenes through organic photoredox-catalyzed radical-radical coupling.

ABSTRACT: We developed a distal C-H functionalization of electron-rich arenes such as alkoxyarenes using diverse coupling partners through organic photoredox catalysis. Our reaction features radical-radical coupling between a cyclohexadienyl radical and various persistent radicals. A range of functional groups, including sp² carbon-based groups such as alkoxycarbonyl and pyridyl, as well as heteroatom-containing groups like sulfonyl, and alkyl groups were successfully introduced.

SUBMITTER: Goto Y 

PROVIDER: S-EPMC11792067 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature