Invasive Mould Infections Following Combat-Related Injuries-A Retrospective Cohort Study.

ABSTRACT:

Background

Available data on combat wound-related invasive mould infections (IMIs) are limited.

Objectives

We aimed to describe the characteristics and outcomes of IMIs in casualties of a recent conflict.

Patients/methods

A retrospective study including hospitalised patients with combat-related injuries, fulfilling criteria for wound-related IMI based on Trauma Infectious Disease Outcomes Study definitions. Patient and injury characteristics, management and outcomes are described and compared to previous cohorts. Mould isolates and susceptibility testing results, including the novel agent manogepix, are reported.

Results

Overall, 31 patients (69 mould isolates) were included-resulting in an IMI incidence rate of 1.9%. Blast was the most common injury mechanism

SUBMITTER: Hoffman T 

PROVIDER: S-EPMC11792097 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature