Reproduction outcomes and prognostic significance of pregnancy after nasopharyngeal carcinoma treatment.

ABSTRACT:

Objective

Many female patients with nasopharyngeal carcinoma (NPC) desire to reproduce after treatment. To evaluate the outcomes of subsequent pregnancy after NPC and explore the prognostic effects of pregnancy in women.

Methods

Female patients with locoregional NPC were included, and their pregnancy status, newborn information, and obstetric information were collected. Pregnant patients after therapy were matched to non-pregnant patients for survival analysis and overall survival (OS), disease-free survival (DFS), distant metastasis-free survival (DMFS), and locoregional relapse-free survival (LRFS) were assessed.

Results

Of 895 patients, 79 conceived after NPC treatment. Of these, 52 women successfully delivered, and the rest had abortions. No abnormalities were rec

SUBMITTER: Luo M 

PROVIDER: S-EPMC11792128 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature